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Efsa feedap technical guidance for hazard

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Any toxigenic potential in other species appears far more likely to arise from the production of surfactins. The selection of strains belonging to the B. Abstract Bacillus species are used in animal production directly as microbial feed additives or as the source of other feed additives, notably enzymes. Bacillus species, enterotoxin production, emetic toxin, cereulide, surfactin-like lipopeptides. You are here Home Scientific Outputs at a glance Technical guidance on Bacillus safety Technical Guidance on the assessment of the toxigenic potential of Bacillus species used in animal nutrition. Question Number :. Skip to main content.

  • Guidance on consumer safety European Food Safety Authority
  • Feed additive applications regulations and guidance European Food
  • Guidance on user safety European Food Safety Authority
  • Guidance on Bacillus safety European Food Safety Authority

  • Technical Guidance for assessing the safety of feed additives for the environment​. First published in the EFSA Journal: 29 October Adopted: 22 October. Note: This scientific opinion has been replaced by Guidance on the assessment of the toxigenic potential of Bacillus species used in animal.

    Technical guidance: Tolerance and efficacy studies in target animals.

    Video: Efsa feedap technical guidance for hazard

    First published in the EFSA Journal: 23 May [email protected]
    Applicants seeking regulatory approval for strains of Bacillus species have relied for guidance on how to assess any toxigenic potential on a SCAN opinion published in Any toxigenic potential in other species appears far more likely to arise from the production of surfactins. Skip to main content. The principal safety concern for consumers and, to a lesser extent livestock, associated with Bacillus is a capacity for toxin production.

    Video: Efsa feedap technical guidance for hazard

    EFSA Journal ;12 5 EFSA Journal ;9 11

    images efsa feedap technical guidance for hazard
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    Question Number :. Contact :.

    Guidance on consumer safety European Food Safety Authority

    It now seems unlikely that B. Bacillus species are used in animal production directly as microbial feed additives or as the source of other feed additives, notably enzymes. Bacillus species, enterotoxin production, emetic toxin, cereulide, surfactin-like lipopeptides. Skip to main content. On request from :.

    Guidance on studies concerning the safety of use of the additive for users/ First published in the EFSA Journal: [email protected] EU legislation and EFSA guidance documents detail how to compile dossiers for Biological hazard · Feed additives EFSA's guidance is updated regularly so applicants should check they are using the latest version before applying.

    Feed additive applications regulations and guidance European Food

    First published in the EFSA Journal: To avoid confusion, the original version of the Guidance has been removed [email protected]
    However, a single cytotoxicity assay is retained to confirm the expected absence of B. Any toxigenic potential in other species appears far more likely to arise from the production of surfactins. Bacillus species, toxin production, surfactins, enterotoxins. On request from :. A test for haemolysis coupled with PCR detection of non-ribosomal peptide synthase genes seems adequate to identify surfactin-positive strains.

    images efsa feedap technical guidance for hazard
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    Contact :.

    Guidance on user safety European Food Safety Authority

    If there is evidence of homology, the non-functionality of the genes e. Abstract Applicants seeking regulatory approval for strains of Bacillus species have relied for guidance on how to assess any toxigenic potential on a SCAN opinion published in On request from :.

    Skip to main content. Any toxigenic potential in other species appears far more likely to arise from the production of surfactins.

    Guidance on the assessment of the toxigenic potential of Bacillus species First published in the EFSA Journal: [email protected] Technical guidance - Update of the criteria used in the assessment of bacterial resistance to antibiotics of human or veterinary importance. Guidance for establishing the safety of additives for the consumer.

    Guidance on Bacillus safety European Food Safety Authority

    First published in the EFSA Journal: [email protected] doi.
    The selection of strains belonging to the B. Subsequent to this opinion there have been significant developments in the knowledge of the nature of the toxins found in Bacillus species and their prevalence. Question Number :. If there is evidence of homology with genes encoding toxins then their non-functionality mutation, deletion, etc. EFSA Journal ;12 5 On request from :.

    images efsa feedap technical guidance for hazard
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    In the absence of animal models shown to be able to distinguish hazardous from non hazardous strains, the FEEDAP Panel relies on the use of in vitro cell-based methods to detect evidence of a cytotoxic effect.

    EFSA Journal ;12 5 If, however, they are proposed then it is recommended that the full genome should be sequenced and a bioinformatic analysis made. However, the capacity for toxin production and the nature of the toxins produced is unevenly distributed over the genus, occurring frequently in some species and more rarely in others.

    Adopted :. EFSA Journal ;9 11

    1 thoughts on “Efsa feedap technical guidance for hazard”

    1. Kerisar:

      Contact :. Bacillus species are used in animal production directly as microbial feed additives or as the source of other feed additives, notably enzymes.